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Dupilumab Improves Health-Related Quality of Life and Respiratory Symptoms in Patients With COPD and Type 2 Inflammation
A pooled analysis of two phase 3 trials suggests that dupilumab demonstrated improvements in St. George’s Respiratory Questionnaire and Evaluating Respiratory Symptoms in COPD total and domain scores in patients with COPD and type 2 inflammation.
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Modified Cuff Leak Test for Predicting the Risk of Reintubation in Patients With Invasive Mechanical Ventilation
A multicenter, single-blind, randomized controlled trial suggests that the modified cuff leak test approach might better predict postextubation stridor within 24 hours of extubation, but it was not shown to help decrease the reintubation incidence and mortality.
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Estimating the Causal Effect of Double-Blind Peer Review for a Pulmonary, Critical Care, and Sleep Medicine Journal
A retrospective study of manuscripts submitted to the journal CHEST from January 2020 to June 2024 indicates that double-blind peer review did not differentially affect authors by gender but did by presumed English fluency.
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Diagnostic Yield and Synergistic Impact of Needle Aspiration and Forceps Biopsy With Electromagnetic Navigation Bronchoscopy for Peripheral Pulmonary Lesions
A randomized controlled trial suggests that the combination of electromagnetic navigation bronchoscopy-guided needle aspiration and forceps biopsy may significantly improve the overall diagnostic yield and sensitivity compared with either approach alone for diagnosing pulmonary lesions with a favorable safety profile.
Interventions to Improve Adherence to Clinical Guidelines for the Management and Follow-Up of Pulmonary Nodules
A systematic review finds that it is possible to significantly improve follow-up of patients with pulmonary nodules; however, variability in outcomes and limitations in study quality underscore the need for further evaluations using rigorous randomized controlled trials.
Effect of Famotidine on Outcomes in Pulmonary Arterial Hypertension
A randomized controlled trial argues against the routine use of famotidine 20 mg daily as an adjunct therapy for the treatment of pulmonary arterial hypertension.
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XALOC-1: Clinical Remission Over 2 Years With Benralizumab in Severe Eosinophilic Asthma
Trajectories of Interferon-Gamma Release Assay Results Over 2 Years in Independent Cohorts From China, South Africa, Tanzania, and the United States
Preserved Ratio Impaired Spirometry Is an Important Risk Factor for Development of COPD, Also in Those Who Do Not Smoke
Use of High-Dose Hydroxocobalamin for Septic Shock
Diagnostic Evaluation and Clinical Findings in Children With Persistent Tachypnea of Infancy/Neuroendocrine Cell Hyperplasia of Infancy: A European Multicenter Retrospective Study
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Watch the latest CHEST journal webinar.
Journal CHEST® authors, Daniel Lachant, DO, and R. James White, MD, PhD, discuss the article, "Cardiac Effort to Compare Clinic and Remote 6-Minute Walk Testing in Pulmonary Arterial Hypertension."
Moderator: Nicholas A. Kolaitis, MD, MAS
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Editor in Chief: Peter J. Mazzone, MD, MPH, FCCP
Published monthly Archived back to 1935
Submission/Review Stats
Acceptance rate: 8-10% for Original Research
Time to first decision: 3 weeks
Acceptance to publication: 2 to 3 weeks to Online First, 5 months to print
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