CHESTGuidelines & Topic CollectionsThe Rapidly Changing Treatment Paradigm for Stage III Non-Small Cell Lung Cancer

The Rapidly Changing Treatment Paradigm for Stage III Non-Small Cell Lung Cancer

Recorded: August 27, 2025

Stage III non-small cell lung cancer (NSCLC) is a commonly encountered disease among those diagnosed with lung cancer. Over the past five years, there have been significant changes in how this disease is managed, including adjuvant targeted therapy after surgical resection and neoadjuvant chemoimmunotherapy before surgery, along with a myriad of approaches in those who are either nonoperable or nonresectable. All approaches rely on preoperative comprehensive genomic profiling of diagnostic specimens prior to making treatment decisions. This webinar reviews all aspects of treatment for stage III NSCLC, with special emphasis on the multidisciplinary approach to this disease.

This non-CME education is brought to you by CHEST and sponsored by AstraZeneca.

Watch Part 1: Early-Stage NSCLC: Advances in Diagnosis, Tissue Acquisition, and Treatment »


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Moderator

Gerard A. Silvestri, MD, MS, Master FCCP

Hillenbrand Distinguished University Professor
Senior Vice-Chair of Faculty
Development Department of Medicine
Medical University of South Carolina
Charleston, SC


Panelist

Jessica S. Donington, MD, MSCR

Professor Surgery
Chief Section of Thoracic Surgery
University of Chicago
Chicago, IL


Panelist

Mariam Alexander, MD, PhD

Assistant Professor
Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine
Medical University of South Carolina
Charleston, SC


Panelist

Anurag Singh, MD

Director, Radiation Research
Director, Head & Neck and Lymphoma Radiation Services
Associate Dean of Graduate Medical Education, Radiation Medicine
Roswell Park Comprehensive Cancer Center
New York


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