Guardrails, Gray Areas, and a Spiculated Surprise: A Stage I Lung Cancer Case
ABOUT THIS EPISODE
Originally aired: December 16, 2025
A 49-year-old individual who never smoked learns a routine scan has uncovered a suspicious lung lesion—low PET uptake, a negative bronchoscopy, and “stable” imaging… yet clinical instincts say, “Don’t ignore this.” In this story-driven episode, host Lisa Moores, MD, FCCP, is joined by CHEST Guideline Chair John Howington, MD, MBA, FCCP, and thoracic surgeon Sudish Murthy, MD, PhD, FCCP, to walk through what to do when the data conflict and the stakes are real.
Together, they translate the CHEST guideline “guardrails” into bedside decision-making: when surveillance stops being safe, why minimally invasive surgery matters, and how lung-sparing resection can deliver an oncologically sound plan while preserving future options.
This is the first of three episodes on CHEST guideline recommendations in lung cancer.
EPISODE 2 » | EPISODE 3 »
HOST
Lisa Moores, MD, FCCP
PANELISTS
Guideline Chair: John Howington, MD, MBA, FCCP
Case Guest: Sudish Murthy, MD, PhD, FCCP